Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.
作者： Jun Ishikawa , Tsuneyasu Kaisho , Hitoshi Tomizawa , Byung Ok Lee , Yoshiko Kobune
DOI: 10.1016/0888-7543(95)80171-H
关键词:
摘要: Bone marrow stromal cells regulate B-cell growth and development through their surface molecules cytokines. In this study, we generated a mAb, RS38, that recognized novel human membrane protein, BST-2, expressed on bone cell lines synovial lines. We cloned cDNA encoding BST-2 from rheumatoid arthritis-derived line. is 30- to 36-kDa type II transmembrane consisting of 180 amino acids. The gene (HGMW-approved symbol BST2) located chromosome 19p13.2. not only certain but also various normal tissues, although its expression pattern different another molecule, BST-1. fibroblast facilitated the cell-dependent murine marrow-derived pre-B-cell line, DW34. results suggest may be involved in growth.
osti.gov
elsevier.com
sci-hub.se 参考文章(46)
PC Kierney, K Dorshkind, B lymphocyte precursors and myeloid progenitors survive in diffusion chamber cultures but B cell differentiation requires close association with stromal cells. Blood. ,vol. 70, pp. 1418- 1424 ,(1987) , 10.1182/BLOOD.V70.5.1418.1418
KS Landreth, R Narayanan, K Dorshkind, Insulin-like growth factor-I regulates pro-B cell differentiation Blood. ,vol. 80, pp. 1207- 1212 ,(1992) , 10.1182/BLOOD.V80.5.1207.1207
JM Gimble, C Pietrangeli, A Henley, MA Dorheim, J Silver, A Namen, M Takeichi, C Goridis, PW Kincade, Characterization of murine bone marrow and spleen-derived stromal cells: analysis of leukocyte marker and growth factor mRNA transcript levels. Blood. ,vol. 74, pp. 303- 311 ,(1989) , 10.1182/BLOOD.V74.1.303.303
R. J. Scheper, S. T. Pals, C. J. L. M. Meijer, G. Koopman, E. Horst, W. Newmann, A. C. H. M. Van Dinther-Janssen, The VLA-4/VCAM-1 pathway is involved in lymphocyte adhesion to endothelium in rheumatoid synovium. Journal of Immunology. ,vol. 147, pp. 4207- 4210 ,(1991)
G S Firestein, M J Elices, J Morales-Ducret, N J Zvaifler, E Wayner, J M Alvaro-Gracia, Alpha 4/beta 1 integrin (VLA-4) ligands in arthritis. Vascular cell adhesion molecule-1 expression in synovium and on fibroblast-like synoviocytes. Journal of Immunology. ,vol. 149, pp. 1424- 1431 ,(1992)
Krisztina M. Zsebo, Keith E. Langley, Ian K. McNiece, The role of recombinant stem cell factor in early B cell development: Synergistic interaction with IL-7 Journal of Immunology. ,vol. 146, pp. 3785- 3790 ,(1991)
K Oritani, T Kaisho, T Hirano, J Ishikawa, O Muraoka, T Ochi, M Tanabe, Human bone marrow stromal cell lines from myeloma and rheumatoid arthritis that can support murine pre-B cell growth. Journal of Immunology. ,vol. 149, pp. 4088- 4095 ,(1992)
A Varas, P E Funk, P L Witte, Activity of stem cell factor and IL-7 in combination on normal bone marrow B lineage cells. Journal of Immunology. ,vol. 150, pp. 748- 752 ,(1993)
R Palacios, J Samaridis, Fetal liver pro-B and pre-B lymphocyte clones : expression of lymphoid-specific genes, surface markers, growth requirements, colonization of the bone marrow, and generation of B lymphocytes in vivo and in vitro Molecular and Cellular Biology. ,vol. 12, pp. 518- 530 ,(1992) , 10.1128/MCB.12.2.518
S Jalkanen, M Salmi, L Airas, Lymphocyte-vascular adhesion protein-2 is a novel 70-kDa molecule involved in lymphocyte adhesion to vascular endothelium. Journal of Immunology. ,vol. 151, pp. 4228- 4238 ,(1993)