MANAGEMENT OF INFLAMMATORY BOWEL DISEASE AND EXPERIMENTAL MODELS ESTABLISHED FOR EVALUATION- AN UPDATE

摘要: Inflammatory bowel diseases (IBD) include Ulcerative colitis (UC), an inflammatory disease of the large intestine and Crohn‟s (CD). is ulcers form in inner lining or mucosa colon rectum, often resulting diarrhea, blood, pus. The use conventional steroids, glucocorticoids TNF-α inhibitors are found highly effective treating IBD but their associated with some adverse effects. Therefore, importance using natural products has increased, as they have interest discovering efficient new drugs less Natural desirable for treatment diseases, such ulcerative Crohn's disease. However, there limited controlled evidences indicating efficacy traditional Chinese medicines, aloe vera gel, wheat grass juice, Boswellia serrata etc., UC. Many experimental models TNBS model, hapten induced etc. established evaluation IBD. This review focuses on management by medicinal plants, synthetic methods