Adrenergic Receptor Function is Different in Male and Female Patients with Essential Hypertension
作者： Marian S. Kafka , C. Raymond Lake , Hans-Georg Gullner , John F. Tallman , Frederic C. Bartter
DOI: 10.3109/10641967909068628
关键词:
摘要: As plasma norepinephrine (NE) levels may be similar in hypertensive and normotensive subjects, the sensitivity of adrenergic receptors was investigated patients with essential hypertension subjects age sex. Alpha-adrenergic receptor measured platelets by specific binding [3H] dihydroergocryptine NE inhibition prostaglandin E1(PGE1)-stimulated cyclic AMP (cAMP) production. The number alpha-adrenergic from women 1.5 times that ones, no differences between or men affinity for [3H]dihydroergocryptine. PGE1-stimulated cAMP production half as great men, while women. dihydroergo-cryptine female hypertensives, ...
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