Omega-6 and Omega-3 Polyunsaturated Fatty Acids and Allergic Diseases in Infancy and Childhood

摘要: There may be a causal relationship between intake of n-6 polyunsaturated fatty acids (PUFAs) and childhood allergic diseases. This can explained by plausible biological mechanisms involving eicosanoid mediators produced from the PUFA arachidonic acid. Long chain n-3 PUFAs are found in fish oils. These act to oppose actions PUFAs. Thus, it is considered that will lower risk developing In support this, protective associations have been reported maternal during pregnancy outcomes infants children those pregnancies. However, studies infancy or inconsistent, although some association. Supplementing pregnant women with oil induce immunologic changes cord blood. supplementation has decrease sensitisation common food allergens prevalence severity atopic dermatitis first year life. The effect last until adolescence offspring. Fish manifestations disease, this benefit not persist. Whether useful therapy asthma receiving standard clear performed date requires further exploration.