Disturbances of serine and glycine metabolism as a cause of episodic acute polymorphous psychoses

摘要: textabstractPsychiatrists are frequently confronted with psychoses that difficult to classify. Many forms of these atypical have been described in European literature. They often an acute onset and a tendency towards complete remission, albeit episodic course. Rich, multiform symptomatology is noted sometimes addition to altered states consciousness. In patients grossly impaired consciousness the psychiatrist has also to consider whether such psychosis is due organic factors or functional (I). Even when morphologically demonstrable excluded, the possibility reaction brain subtle toxic disturbing normal physico-chemical equilibrium without causing cellular damage be taken into account. An intermittent production toxins liver an attractive concept for many researchers understand account the endogenous (2). In this thesis attempt made provide clinical evidence endogenous synthesis which causally related some types the atypical psychoses. The findings led new classification group of poorly defined previously unclassifiable