Logistic regression analysis of small round cell neoplasms: A cytologic study

作者: Lester J. Layfield , Katharine Liu , Richard K. Dodge

DOI: 10.1002/(SICI)1097-0339(199905)20:5<271::AID-DC5>3.0.CO;2-5

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摘要: The diagnosis of small round cell neoplasms (SRCN) in children is difficult by both histologic and cytologic methods. These are unified morphologically the scanty cytoplasm surrounding relatively nuclei containing a primitive chromatin pattern. Further categorization achieved histologically recognition architectural differentiation cytoplasmic features. Numerous series case reports documenting features SRCN have been published English-language literature, but few studies statistically analyzed diagnostic utility these Our logistic regression analysis 59 cases indicates that presence an extremely favors Ewing's sarcoma (P = 0.004), as does positive expression vacuoles 0.02). Strap or tadpole cells closely correlate with rhabdomyosarcoma < 0.001). rosettes strongly supports neuroblastoma Wilms' tumor confirmed tubules lymphoglandular bodies lymphoma While some highly correlated specific SRCN, not invariably present, definitive may require immunohistochemical ultrastructural performed on block material.

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