Morphometric study of the glomerular population in the mouse olfactory bulb: Numerical density and size distribution along the rostrocaudal axis

摘要: A morphometric study of the glomerular population in olfactory bulb mouse has been carried out by using stereological methods. On basis assumption that is a polydispersed system spheres, profile distributions obtained from measurements were subjected to mathematical unfolding procedure obtain actual size distribution. We used distribution-free method account for combined effects overprojection due section thickness and truncation (two missing mechanisms). Results proved better than those directly without analysis. Several new findings obtained. First, significant variations glomerulus sizes found along rostrocaudal axis. The glomeruli are larger middle region bulb, whereas their numerical density decreases same region. Moreover, homogeneous In other words, relative surface occupied periglomerular cells layer invariant. As consequence, it may be concluded inversely correlated. Thus, since region, number per unit volume logically smaller this area. Finally, computerization all these data led us estimate (1,810 +/- 41) mouse. order get comparative idea advantages disadvantages, standard methods present determine number. Functional interpretations axis discussed with respect ontogenetic morphofunctional elsewhere.