A low technology emanator treated with the volatile pyrethroid transfluthrin confers long term protection against outdoor biting vectors of lymphatic filariasis, arboviruses and malaria.

摘要: The vapor phase of the volatile pyrethroid transfluthrin incapacitates mosquitoes and prevents them from feeding. Although existing emanator products for delivering pyrethroids protect against outdoor mosquito bites, they are too short-lived to be practical or affordable routine use in low-income settings. New emanators, comprised simply treated hessian fabric strips, have recently proven highly protective outdoor-biting vectors lymphatic filariasis, arboviruses malaria, but their full lifespan, minimum dose requirements, range protection not previously been assessed.The effects transfluthrin-treated strips upon biting exposure users nearby non-users, as well dependence treatment dose, were measured outdoors rural Tanzania using human landing catches (HLC). Strips with 10ml prevented at least three quarters (p 90% bites on warmer nights higher evaporation rates, one year. this high also reduced non-users a distance up 5m An. arabiensis < 0.001) 2m Mansonia spp. = 0.008), provided no Culex No evidence increased risk caused by diversion unprotected individuals, was found any within an 80m radius. A only 1ml equivalent arabiensis, over 6 months 0.001). Transfluthrin-treated emanators provide safe, affordable, long-term several different pathogen-transmitting taxa that attack humans outdoors, where usually active cannot protected bed nets residual sprays conventional, solid-phase insecticides.