Prevalence of Hepatitis C Virus Antibodies Among Blood Donors in Northern Jordan(Brief Communications )

摘要: Background and Objectives: Hepatitis C Virus (HCV) remains the most common cause of transfusion-related hepatitis in world. Despite accurate screening methods introduced after discovery virus about two decades ago, blood products transfusion an important source HCV infection Jordan. The worldwide prevalence among donors is variable, ranging between 0.17 20%. main objective this study was to determine positive serology for population Northern different genotypes individuals a secondary study. Study Population Methods: From January 2004 till June 2006, total 14,236 (13666 males 570 females) donated at King Abdullah University Hospital. A third-generation Enzyme- Linked Immuno-Sorbent Assay (ELISA) test system using commercial Diasorin kit, ETI-AB-HCVK- 4(N0146, N0147) which used screen all antibodies HCV. performed strictly as per manufacturer's instructions. Data were collected from bank database. Samples detectable RNA submitted genotyping Real Time PCR. (MX 4000) method. Results: 29 (27 males, 2 tested anti-HCV antibodies, with overall 0.20%. seroprevalence females approximately double that (0.35% vs 0.19%). prevalent genotype type 4. Conclusion: This indicates North Jordan lower than other regions country. Overall, our national healthy (0.2%-0.79%) concordant results epidemiological studies Western World (0.17-0.1.5%). cohort 4.