Survival and prognostic factors for adrenocortical carcinoma: a single institution experience

摘要: Adrenocortical carcinoma (ACC) is aggressive, but rare tumours that have not been sufficiently studied. The aim of our study was to present the demographic and clinical characteristics patients with ACC, determine overall survival rates, analyse effect prognostic factors on survival, as well identify favorable unfavourable predictors survival. included 72 (42 women 30 men) ACC. We analysed value patients, tumour characteristics, therapy administered rates. Kaplan-Meier curves log-rank test were used estimate specific probabilities Cox regression model independent for had mean age 50 years. 1-, 5-, 10-year in ACC 52.5 %, 41.1 %, 16.4 %, respectively. median time 36 months. results multivariate analysis showed presence lymphatic metastases (HR = 7.37, 95 % CI = 2.31-23.48, p = 0.001) mitotane (HR = 0.11, CI = 0.04-0.27, metastasis an factor, while postoperative a factor