Prediction of respiratory distress syndrome by the novel dipalmitoyl phosphatidylcholine test
作者： J Alvarez
DOI: 10.1016/0029-7844(95)00462-9
关键词:
摘要: Objective: To determine the accuracy of a new test that measures concentration in amniotic fluid (AF) dipalmitoyl phosphatidylcholine (DPPC) predicting respiratory distress syndrome (RDS). Methods: The neonatal status 176 newborns delivered within 72 hours sampling was correlated with DPPC, fluorescence polarization (TDx-FLM), lecithin-sphingomyelin ratio (L/S), and phosphatidylglycerol (Amniostat-FLM) AF. Results: Thirty infants developed RDS (17%), all correctly predicted DPPC values less than 12 μg/mL (sensitivity 100%). Only six 146 cases no had (specificity 96%). overall 98% compared 70% for TDx-FLM, 71% L/S, 67% Amniostat-FLM. Receiver operating characteristic analysis area 0.98 ± 0.01, indicating is superior to both TDx-FLM L/S tests. Conclusion: an accurate predictor fetal lung maturity.
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