The Pictet–Spengler Reaction in Nature and in Organic Chemistry

作者: Joachim Stöckigt , Andrey P. Antonchick , Fangrui Wu , Herbert Waldmann

DOI: 10.1002/ANIE.201008071

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摘要: Alkaloids are an important class of natural products that widely distributed in nature and produced by a large variety organisms. They have wide spectrum biological activity for many years were used folk medicine. These days, alkaloids also numerous applications medicine as therapeutic agents. The importance these inspiring drug discovery programs is proven and, therefore, their continued synthesis significant interest. condensation discovered Pictet Spengler the most method alkaloid scaffolds. power this has been convincingly construction stereochemicaly structurally complex alkaloids.

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