Association of F18-fluoro-ethyl-tyrosin uptake and 5-aminolevulinic acid-induced fluorescence in gliomas

作者: Florian Stockhammer , Martin Misch , Peter Horn , Arend Koch , Nyuyki Fonyuy

DOI: 10.1007/S00701-009-0462-7

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摘要: Purpose Malignant gliomas are highly infiltrative tumours with a fatal prognosis. F18-fluoroethyl-tyrosine (FET)-positron emission tomography (PET) often reveals broader extension of these compared contrast-enhanced magnetic resonance imaging (MRI). Complete resection the contrast-enhancing lesion is aspired. Fluorescence-guided using 5-aminolevulinic acid (5-ALA) improved extent resection. In this study, we investigated whether FET uptake correlates 5-ALA-induced fluorescence.

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