Radical scavenging, prolyl endopeptidase inhibitory, and antimicrobial potential of a cultured Himalayan lichen Cetrelia olivetorum.

摘要: AbstractContext: Lichens are source of natural bioactive compounds which traditionally used to cure a variety ailments.Objective: The objective this study is assess free radical scavenging, prolyl endopeptidase inhibitory (PEPI), and antimicrobial potential high altitude lichen species Cetrelia olivetorum (Nyl.) W. L. Culb. & C. F. Culb (Parmeliaceae).Materials methods: Lichen has been cultured in vitro, optimized culture conditions were implemented bioreactor obtain quantity biomass for the PEPI, activities. Radical scavenging activity methanol extract (MECO) was tested at 100 µg/mL, PEPI 25 50 µg/mL, 5, 25, 50, 100 µg/mL conc. All biological activities thallus its derived evaluated spectrophotometrically.Results: Murashige Skoog medium supplemented with 3% glucose 100 ppb in...