Differences in cardiovascular disease risk factors between Japanese in Japan and Japanese-Americans in Hawaii: the INTERLIPID study.

摘要: Despite increase in serum total cholesterol, high smoking rate, and frequency of adverse blood pressure levels Japan, coronary heart disease (CHD) incidence mortality apparently remain substantially lower at all ages Japan than the US other Western societies. To better understand these differences, we compared CHD biomedical risk factors dietary variables Japanese living 3rd 4th generation emigrants a primarily lifestyle Hawaii, an ancillary study INTERMAP. Men women aged 40-59 years were examined by common standardized methods-four samples (574 men, 571 women) Japanese-American sample Hawaii (136 131 women). Average systolic (SBP) diastolic (DBP) pressures significantly higher men Hawaii; there no significant differences women. The treatment rate hypertension was much Hawaii. Smoking prevalence higher, markedly so for Body mass index, low-density lipoprotein HbA1c, fibrinogen high-density cholesterol Japan. Total fat, saturated fatty acid intake, Keys lipid score Polyunsaturated/saturated ratio omega-3 intake In conclusion, several, especially lipid, generally These smaller between They may partly explain industrialized countries.