Resectable liver metastases from colorectal cancer: where we are now and where do we go from here?

摘要: SUMMARY Liver metastases from colorectal cancer represent a peculiar clinical scenario in everyday practice, since treatment should achieve long-term survival or even cure selected patients. Presentation may vary between single cases, ranging easily resectable lesions to more advanced metastatic spreading for which surgery can only be considered after major tumor shrinkage. For liver metastases, remains the essential step curative approach disease, though different ablative procedures as valuable alternatives certain subsets. Postoperative perioperative chemotherapy further improve outcome, benefits and harms related toxicity carefully balanced each patient. A comprehensive multidisciplinary assessment of patient- tumor-related features key complement aspects with biological characterization framework personalized therapeutic appr...