[Health hazards from exposure to ortho-phthalaldehyde, a disinfectant for endoscopes, and preventive measures for health care workers].

作者: Hiroshi Fujita , Yasuyuki Sawada , Masanori Ogawa , Yoko Endo

DOI: 10.1539/SANGYOEISEI.49.1

关键词:

摘要: Recently, the use of ortho-phthalaldehyde(OPA)has been increasing as an alternative to glutaraldehyde(GA)for endoscope disinfection. We detected development bronchial asthma and contact dermatitis in health care workers(HCW)employed endoscopy unit. After performing examinations work environment measurements, we took preventative measures against these diseases. Seventeen 70 HCW had experienced skin, respiratory, or eye symptoms. Contact occurred 4 workers, one whom also developed asthma. OPA concentration air unit ranged from 0.06 2.01 ppb. The highest was obtained while cover a bucket for dipping instruments opened. Dipping then discontinued, personal protector provided each local ventilation devices auto-washers, education performed HCW. At periodic examination next year, two 83 described mild irritation, but no bronchitis newly developed. This study clearly revealed that despite very low level air, symptoms skin respiratory tract can occur. Spreading substitute GA may result serious risks To prevent hazards exposure, wearing fully automated washing machine with exhauster are required.

参考文章(13)
L. Maestri, A. Alessio, L. Zambianchi, S. Negri, A. Marone Bianco, L. Lodola, Carlo Marena, [Monitoring air dispersed concentrations of aldehydes during the use of ortho-phthalaldehyde and glutaraldehyde for high disinfection of endoscopes]. Giornale italiano di medicina del lavoro ed ergonomia. ,vol. 25, pp. 131- 136 ,(2003)
Tomoko Takigawa, Yoko Endo, Effects of glutaraldehyde exposure on human health. Journal of Occupational Health. ,vol. 48, pp. 75- 87 ,(2006) , 10.1539/JOH.48.75
S. E. Walsh, J‐Y. Maillard, A. D. Russell, Ortho-phthalaldehyde: a possible alternative to glutaraldehyde for high level disinfection. Journal of Applied Microbiology. ,vol. 86, pp. 1039- 1046 ,(1999) , 10.1046/J.1365-2672.1999.00791.X
Matthew P. Shaffer, Donald V. Belsito, Allergic contact dermatitis from glutaraldehyde in health-care workers Contact Dermatitis. ,vol. 43, pp. 150- 156 ,(2000) , 10.1034/J.1600-0536.2000.043003150.X
Hiroshi Fujita, Masanori Ogawa, Yoko Endo, A Case of Occupational Bronchial Asthma and Contact Dermatitis Caused by ortho‐Phthalaldehyde Exposure in a Medical Worker Journal of Occupational Health. ,vol. 48, pp. 413- 416 ,(2006) , 10.1539/JOH.48.413
Steven G. Venticinque, Vikram S. Kashyap, Robert J. O???Connell, Chemical Burn Injury Secondary to Intraoperative Transesophageal Echocardiography Anesthesia & Analgesia. ,vol. 97, pp. 1260- 1261 ,(2003) , 10.1213/01.ANE.0000083641.58267.0C