Electron Microscope Study of a Cell-Free Induced Leukemia of the Mouse: A Preliminary Report

作者: Étienne de Harven , Charlotte Friend

DOI: 10.1083/JCB.4.2.151

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摘要: Preliminary results of an electron microscope study a leukemia the mouse transmissible by cell-free filtrates are reported. In twelve out forty-seven specimens examined, virus-like particles were observed. So far, these have not been observed in control, non-leukemic animals. They located inside cytoplasm leukemic cells which infiltrate spleen or liver. Their diameter is approximately 78 mµ. resemblance to other recently described different tumors stressed. significance and, correlation with ultrafiltration data, their possible etiological meaning discussed.

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