Hematopoietic Stem Cell Transplantation for Malignant Solid Tumors in Children

作者: Toshihisa Tsuruta

DOI: 10.5772/25848

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摘要: The prognosis of malignant solid tumors in children has been improved by multidisciplinary therapy involving surgery, radiotherapy and chemotherapy. High-dose chemotherapy (HDC) followed autologous (Auto) or allogeneic (Allo) hematopoietic stem cell transplantation (HSCT) contributed significantly to improvements the high-risk chemosensitive tumors. It utilized many kinds pediatric malignancies, not only but also such as neuroblastoma, brain tumors, Ewing’s sarcoma, osteosarcoma, Wilms’ tumor, rhabdomyosarcoma, hepatoblastoma, retinoblastoma. Fig, 1 shows numbers cases which HSCT was used for Japan. When is patients with there are several treatment objectives. First, it can be intended a curative acting on minimal residual cells after

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