The influence of hypotensive drugs on the taste sensitivity in patients with primary hypertension.

摘要: Numerous hypotensive drugs result in decreasing the taste sensitivity or total loss of perception. The aim this study was to evaluate influence selected groups used combined treatment patients suffering from primary arterial hypertension. con- ducted a group 84 aged 30-60, including 43 women and 41 men. were divided into four depending on applied following regimes: diuretic + β-blocker, β-blocker ACE-I, ACE-I diuretic, calcium channel blocker. involved also control 20 healthy people (without medications) 10 Taste evaluated by two methods: chemosensory electrogustometric. Chemosensory method asses salt sweet tastes with use increasing centrations saccharose water solutions (0.012-0.041 mmol/L) sodium chloride (0.008- 0.068 mmol/L). Electrogustometric thresholds established electrogustometer. minimal intensity current, which stimulates nerve endings stimuli-transmitting nerves determined areas tongue: at apex sides. By different methods evaluation it shown that analyzed affect patients. It observed had higher than Introducing ther- apy significantly reduced electrogustometric