Creating, Modeling, and Visualizing Metabolic Networks

摘要: Metabolic networks combine metabolism and regulation. These complex are difficult to understand create due the diverse types of information that need be represented. This chapter describes a suite interlinked tools for developing, displaying, modeling metabolic networks. The network interactions database, MetNetDB, contains on regulatory derived from combination web databases input biologists in their area expertise. PathBinderA mines biological “literaturome” by searching new or supporting evidence existing Sentences abstracts ranked terms likelihood an interaction is described combined with provided other sentences. FCModeler, publicly available software package, enables biologist visualize model maps. FCModeler aids development evaluation hypotheses, provides framework assessing large amounts data captured high-throughput gene expression experiments.