RETICULIN FIBROSIS AND BONE INFARCTION IN ACUTE LEUKEMIA. IMPLICATIONS FOR PROGNOSIS.

作者: DONALD W. KUNDEL , GEORGE BRECHER , GERALD P. BODEY , GEOFFREY M. BRITTIN

DOI: 10.1182/BLOOD.V23.4.526.526

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摘要: Reticulin fibrosis was found in 21 of 40 patients with acute lymphocytic leukemia when marrows were studied sequentially by Vim-Silverman needle biopsies. frequently occurred early the development disease. Mild degrees completely reversible remission, severe usually persisted, even through remissions. Fibrosis appeared to develop during relapse. Duration disease itself had little influence on degree reticulin fibrosis, and collagen seldom followed after many months’ duration. The prognosis their definitely poorer than for group without increased reticulin. virtually always prevented successful marrow biopsies standard technic aspiration. Bone necrosis 11 75 leukemia, but none 53 myelogenous life or at autopsy. major cause bone pain it associated marrow. infarcts not short survival all cases, general that demonstrable infarction.

参考文章(11)
Hamada T, Yumoto T, Hashimoto M, Kikuchi M, Bone marrow in human leukemia. Kyushu journal of medical science. ,vol. 12, pp. 197- 225 ,(1961)
Emil Frei, Emil J. Freireich, Edmund Gehan, Donald Pinkel, James F. Holland, Oleg Selawry, Farid Haurani, Charles L. Spurr, Donald M. Hayes, G. Watson James, Harvey Rothberg, D. Bruce Sodee, R. Wayne Rundles, Leslie R. Schroeder, Barth Hoogstraten, Irving J. Wolman, D. G. Traggis, Talbert Cooper, B. R. Gendel, Franklin Ebaugh, Robert Taylor, Studies of Sequential and Combination Antimetabolite Therapy in Acute Leukemia: 6-Mercaptopurine and Methotrexate Blood. ,vol. 18, pp. 431- 454 ,(1961) , 10.1182/BLOOD.V18.4.431.431
Bradley L. Coley, Norman L. Higinbotham, Harvey P. Groesbeck, Primary reticulum-cell sarcoma of bone; summary of 37 cases. Radiology. ,vol. 55, pp. 641- 658 ,(1950) , 10.1148/55.5.641
LLOYD F. CRAVER, CHANGES OF THE BONES IN THE LEUKEMIAS Archives of Surgery. ,vol. 30, pp. 639- 646 ,(1935) , 10.1001/ARCHSURG.1935.01180100085009
Emil J. Freireich, Edmund A. Gehan, David Sulman, Dane R. Boggs, Emil Frei, The effect of chemotherapy on acute leukemia in the human Journal of Chronic Diseases. ,vol. 14, pp. 593- 608 ,(1961) , 10.1016/0021-9681(61)90118-7
Louis B. Thomas, Claude E. Forkner, Emil Frei, Iii, Byron E. Besse, James R. Stabenau, The skeletal lesions of acute leukemia Cancer. ,vol. 14, pp. 608- 621 ,(1961) , 10.1002/1097-0142(199005/06)14:3<608::AID-CNCR2820140322>3.0.CO;2-X
A. Policard, The conflict of living matter with the mineral world: The pneumoconioses Journal of Clinical Pathology. ,vol. 15, pp. 394- 400 ,(1962) , 10.1136/JCP.15.5.394
DANE R. BOGGS, MAXWELL M. WINTROBE, G E CARTWRIGHT, The acute leukemias. Analysis of 322 cases and review of the literature. Medicine. ,vol. 41, pp. 163- 225 ,(1962) , 10.1097/00005792-196209000-00001
William McFarland, BIOPSY OF BONE MARROW WITH THE VIM-SILVERMAN NEEDLE Journal of the American Medical Association. ,vol. 166, pp. 1464- 1466 ,(1958) , 10.1001/JAMA.1958.62990120004011A