Estrogens and cancer.

摘要: In the article by Dr. Joseph Rogers "Estrogens in Menopause and Postmenopause" publish February 13 issue of Journal he summarily dismisses problem estrogens carcinoma with one sentence a reference to 15 year old paper (Obst. & Gynec. 3:551-572 1954) dealing estrogen its possible carcinogenicity toward endometrium. Surely must be aware concern since then on part several investigators about potential effect acceleration growth early or quiescent breast carcinoma. Moore (New Eng. J. Med 277: 293-296 1967) has called attention fact that both progestins will stimulate dormant metastases. Emerson Jessiman Med. 254: 252=258 1956) stated cancer patient under 65 is readily stimulated estrogens. Pearson et al. (J. Clin. Endocrinol. Metab. 12:926. 1952) showed cyclic estrogenic stimulation lst 1/2 normal menstrual cycle associated clearly demonstrable admirably surveyed literature concerning equivocal value therapy osteoporosis prevention treatment atherosclerosis. He also justly concluded supply no Fountain Youth. It seems contradictory at least recognize hand leading cause death middle aged female possibly curable only stages other propose for control hot flushes widespread use substance widely believed accelerate growth.(FULL TEXT)