Effect of short-term microgravity and long-term hindlimb unloading on rat cardiac mass and function.

作者: Chester A. Ray , Marilyn Vasques , Todd A. Miller , M. Keith Wilkerson , Michael D. Delp

DOI: 10.1152/JAPPL.2001.91.3.1207

关键词:

摘要: The purpose of this study was to test the hypothesis that exposure short-term microgravity or long-term hindlimb unloading induces cardiac atrophy in male Sprague-Dawley rats. For microgravi...

参考文章(40)
Thomas P. Moore, Sam L. Pool, William E. Thornton, Fluid shifts in weightlessness. Aviation, Space, and Environmental Medicine. ,vol. 58, ,(1987)
J. Steskal, C. M. Tipton, C. Johansson, A. R. Hargens, Tissue fluid shift, forelimb loading, and tail tension in tail-suspended rats ,(1984)
M. W. Bungo, D. J. Goldwater, R. L. Popp, H. Sandler, Echocardiographic evaluation of space shuttle crewmembers Journal of Applied Physiology. ,vol. 62, pp. 278- 283 ,(1987) , 10.1152/JAPPL.1987.62.1.278
X. J. Musacchia, G. A. Meininger, D. R. Deavers, Fluid/electrolyte balance and cardiovascular responses: head-down tilted rats. The Physiologist. ,vol. 33, ,(1990)
Charles M. Tipton, Christopher R. Woodman, Craig S. Stump, Jane A. Stump, Zia Rahman, Effect of 29 days of simulated microgravity on maximal oxygen consumption and fat-free mass of rats Aviation, Space, and Environmental Medicine. ,vol. 62, pp. 1147- 1152 ,(1991)
L. Kraft, M. Ruder, R. Grindeland, T. Fast, M. Vasques, Rat maintenance in the Research Animal Holding Facility during the flight of Space Lab 3 The Physiologist. ,vol. 28, ,(1985)
Charles M. Tipton, Christopher R. Woodman, Craig S. Stump, Lisa A. Sebastian, Influences of chemical sympathectomy, demedullation, and hindlimb suspension on the VO2max of rats. Aviation, Space, and Environmental Medicine. ,vol. 63, pp. 193- 199 ,(1992)
J. M. Overton, C. M. Tipton, Effect of hindlimb suspension on cardiovascular responses to sympathomimetics and lower body negative pressure Journal of Applied Physiology. ,vol. 68, pp. 355- 362 ,(1990) , 10.1152/JAPPL.1990.68.1.355
M. A. Goldstein, R. J. Edwards, J. P. Schroeter, Cardiac morphology after conditions of microgravity during Cosmos 2044 Journal of Applied Physiology. ,vol. 73, ,(1992) , 10.1152/JAPPL.1992.73.2.S94