Evidence gaps in economic analyses of hearing healthcare: A systematic review

摘要: Abstract Background Hearing loss is a common and costly medical condition. This systematic review sought to identify evidence gaps in published model-based economic analyses addressing hearing inform model development for an ongoing Lancet Commission. Methods We searched the literature through 14 June 2020 our inclusion criteria included decision cost-effectiveness that addressed diagnosis, treatment, or prevention of loss. Two investigators screened articles at title, abstract, full-text levels. Data were abstracted studies assessed qualities structure, data assumptions, reporting using previously quality scale. Findings Of 1437 identified by search, 117 unique met criteria. Most these set high-income countries (n = 96, 82%). The evaluated interventions screening (n = 35, 30%), cochlear implantation (n = 34, 29%), aid use (n = 28, 24%), vaccination (n = 22, 19%), other (n = 29, 25%); some multiple interventions. Eighty-six reported main outcome quality-adjusted disability-adjusted life-years, 24 which derived their own utility values. majority used tree (n = 72, 62%) Markov (n = 41, 35%) models. Forty-one (35%) incorporated indirect effects. median rating was 92/100 (IQR:72–100). Interpretation large body exploring efficiency healthcare However, remain evaluation low- middle-income countries, as well investigating across lifespan. Additionally, considerable uncertainty remains around productivity benefits values hearing-assisted health states. Future evaluations could address limitations. Funding NCATS 3UL1-TR002553-03S3