Evaluation of the relationship between radiological abnormalities and both pulmonary function and pulmonary hypertension in coal workers' pneumoconiosis.

摘要: Objective:  The aim of this study was to investigate the effect radiological evidence emphysema, and extent interstitial involvement, on lung function pulmonary arterial pressure (PAP) in patients with coal workers’ pneumoconiosis (CWP). Methods:  records 48 suspected CWP were evaluated retrospectively. Pulmonary tests, blood gas analyses right heart catheterization all patients. Radiological scoring according International Labour Organization criteria, emphysema scored by CT scanning. Patients grouped mean PAP (≥20 mm Hg or ≤19 mm Hg). Results:  All showed a mild decrease FEV1/FVC increase FRC. Forty-four per cent developed moderate hypertension. Emphysema scores correlated significantly airflow rates, including FEV1%, FEF25−75%, carbon monoxide diffusing capacity (DLCO)% predicted as well FRC% ratio RV/TLC, which are indices air trapping. Additionally, profusion global significant correlation FEV1/FVC, DLCO% predicted, specific airway conductance smoking. Mean negative FEF50% score. Conclusions:  impairment (mainly disturbance rates trapping) hypertension may be present, even simple form CWP. is likely attributable occurrence emphysema. However, directly related pneumoconiotic nodules, result obliteration vascular bed.