Trastuzumab-DM1: Building a Chemotherapy-Free Road in the Treatment of Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

作者: Steven J. Isakoff , José Baselga

DOI: 10.1200/JCO.2010.31.6679

关键词:

摘要: previously untreated acute myeloid leukemia. Blood 114:326, 2009 (abstr 790) 18. Borthakur G, Jabbour E, Wang X, et al: Effect of front-line therapy with fludarabine, cytarabine, filgrastim, and gemtuzumab ozogamicin (FLAG-GO) on outcome in core-binding factor associated myelogenous leukemia (CBFAML). J Clin Oncol 28:499s, 2010 6552) 19. Lo-Coco F, Cimino Breccia M, Gemtuzumab (Mylotarg) as a single agent for molecularly relapsed promyelocytic 104:1995-1999, 2004 20. Estey EH, Giles FJ, Beran Experience ozogamycin (“mylotarg”) all-trans retinoic acid 99:4222-4224, 2002 21. Diverio D, Sustained molecular remission after low dose gemtuzumab-ozogamicin elderly patients advanced Haematologica 92:1273-1274, 2007 22. Ravandi Jones Effective treatment all-trans-retinoic acid, arsenic trioxide, ozogamicin. 27:504-510, 23. Vogel CL, Cobleigh MA, Tripathy Efficacy safety trastuzumab first-line HER2-overexpressing metastatic breast cancer. 20:719-726, 24. Johnson JR, Cohen Sridhara R, Approval summary erlotinib locally or non-small cell lung cancer failure at least one prior chemotherapy regimen. Cancer Res 11:6414-6421, 2005

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