Mild Hypothermia in Experimental Focal Cerebral Ischemia

摘要: The majority of acute ischemic strokes occur as a result thromboembolism cerebral artery. affected brain tissue, the core, is irreversibly damaged rapidly (within 60 min) after onset vessel occlusion. A larger area surrounding penumbra, has potential to recover most its functions following therapeutic intervention. initial cell loss primarily neuronal. However, if occlusion extended beyond 1 h, penumbra begins be incorporated into where all types are affected. maturation damage in may continue for days or weeks. Thus, stroke outcome determined not only by volume but also extent secondary which influenced swelling, impaired microcirculation, and inflammation (1).