Heat-shock proteins maintain the viability of ATP-deprived cells: what is the mechanism?
作者： Alexander E. Kabakov , Vladimir L. Gabai
DOI: 10.1016/0962-8924(94)90135-X
关键词:
摘要: ATP depletion causes necrosis in mammalian cells. However, a previous heat shock can protect cells from the effects of energy deprivation, probably as result synthesis and accumulation heat-shock proteins (hsps). We propose that hsps ATP-depleted rapid necrotic death by inhibiting aggregation cytoskeletal occurs when is blocked.
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