Chromatin regulation in drug addiction and depression

摘要: Alterations in gene expression are implicated the pathogenesis of several neuropsychiatrie disorders, including drug addiction and depression, increasing evidence indicates that changes neurons, context animal models mediated part by epigenetic mechanisms alter chromatin structure on specific promoters. This review discusses recent findings from behavioral, molecular, bioinformatic approaches being used to understand complex regulation brain drugs abuse stress. These advances promise open up new avenues for improved treatments these disorders.