Clinical and therapeutic features of pulmonary nontuberculous mycobacterial disease, Brazil, 1993-2011.
作者： Borga L , Sampaio Ep , Mello Fc , Duarte Rs , de Mello Kg
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摘要: To identify clinical and therapeutic features of pulmonary nontuberculous mycobacterial (PNTM) disease, we conducted a retrospective analysis patients referred to the Brazilian reference center, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil, who received diagnosis PNTM during 1993–2011 with at least 1 respiratory culture positive for NTM. Associated conditions included bronchiectasis (21.8%), chronic obstructive disease (20.7%), cardiovascular (15.5%), AIDS (9.8%), diabetes hepatitis C (4.6%).Two had Hansen disease; Marfan syndrome. Four species comprised 85.6% NTM infections: Mycobacterium kansasii, 59 cases (33.9%); M. avium complex, 53 (30.4%); abscessus, 23 (13.2%); fortuitum, 14 (8.0%). A total 42 (24.1%) were associated rapidly growing mycobacteria. In countries high prevalence tuberculosis, is likely misdiagnosed as thus showing need improved capacity diagnose well greater awareness prevalence.
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