The effects of sevoflurane and ketamine on intraocular pressure in children during examination under anesthesia

摘要: Purpose We studied the effects on intraocular pressure (IOP) of anesthesia administered during examination under (EUA) in children. Design Randomized clinical trial. Methods This randomized trial compared IOP after inhaled sevoflurane gas to that intramuscular ketamine hydrochloride children undergoing EUA. was measured 30 eyes with TonoPen XL (Mentor, Inc, Norwell, Massachusetts, USA) as soon possible induction (T1) and two, four, six, eight minutes thereafter. At same times, we recorded systolic diastolic blood (SBP, DBP) heart rate (HR). Results Compared mean at T1, group significantly lower for all measurements from two thereafter (mean decrease IOP: minutes=12%, four minutes=19%; six minutes=17%, P ≤ .01). In group, not changed T1 through minutes, whereas it 7% ( = .03). SBP DBP were than onward, HR minutes. Conclusions sedation is more likely represent awake anesthesia. Changes SBP, DBP, caused by suggest hemodynamic alterations may underlie its IOP.