Xenotransplantation: The Transplantation of Organs and Tissues Between Species

摘要: This is a time ofexcitement and progress in the field ofxenotransplantation. The work described this book traces development of science cross-spe cies transplantation, summarizes current state ofour knowledge, focuses on approaches directed toward future clinical application. important question not whether xenotransplantation will succeed, but rather how under what circumstances xenografts provide predictable enough results to warrant fact that best date xenografting were achieved over three decades ago should be matter discouragement, stimulus apply new area work. shortage human organs for transplantation cited frequently as driving force behind increased interest xenotransplantation. an undeniable fact, there are additional potential advantages xenotrans plantation, such ability schedule replacement surgery elective basis modification animals, organs, tissues improve acceptabil ity host. advances basic ofxenotransplantation outlined give hope immunologic barriers overcome transplanted succeed consistently humans. However, if our experience with allografts provides analogy, we may anticipate plagued by failures rewarded successes, often without complete understanding mechan isms involved."