Human health risks associated with dietary exposure to persistent organic pollutants (POPs) in river water in Korea

摘要: Abstract Because of their persistence, bioaccumulation tendency, and toxicity, organochlorine pesticides (OCPs) were banned several decades ago. However, they are still detected in natural water pose a serious risk to human health the environment. In present study, seven OCPs measured river collected from 28 sampling sites between 2010 2011 Yeongsan (YS) Seomjin (SJ) Rivers, Korea. Gas chromatography/high-resolution mass spectrometry (HRMS) was used for chemical analysis. The potential risks consuming fish assessed monitoring region (YS SJ River basins) by measuring residual level OCPs. characterized considering both exposure corresponding cancer slope factors; we incorporated deterministic probabilistic approaches. calculated using Maximum Likelihood Estimation (MLE) method. Risk uncertainty sensitivity performing Monte Carlo Of six OCPs, dieldrin, heptachlor epoxide, hexachlorobenzene exceeded acceptable heavy light consumer groups. associated with these 2.99 × 10 −6 , 5.81 × 10 3.72 × 10 respectively, approach 1.64 × 10 −5 3.36 × 10 −2 5.52 × 10 at 95th percentile approach. there is high three individuals who consume large amounts freshwater may be subject cancer. calculations have over- or underestimated because environmental concentration intake rate use left-censored data.