Positron emission tomography radioligands for in vivo imaging of Aβ plaques

作者: N. Scott Mason , Chester A. Mathis , William E. Klunk

DOI: 10.1002/JLCR.2989

关键词:

摘要: … The development of PET imaging agents for Aβ plaque deposits in AD has primarily been based upon structural modifications of pathology dyes (such as Congo red and thioflavin-T) …

参考文章(61)
Chester Mathis, Charles Laymon, Julie Price, Andrew Newberg, Zheng Zhang, James Mountz, Sanaa Boudhar, ACRIN-PA 4004 study: Comparison of [F-18] flutemetamol and [C-11] PiB in normal control and Alzheimer's subjects The Journal of Nuclear Medicine. ,vol. 52, pp. 116- 116 ,(2011)
Chunying Wu, Victor W. Pike, Yanming Wang, Amyloid imaging: from benchtop to bedside. Current Topics in Developmental Biology. ,vol. 70, pp. 171- 213 ,(2005) , 10.1016/S0070-2153(05)70008-9
G. Brent Irvine, Omar M. El-Agnaf, Ganesh M. Shankar, Dominic M. Walsh, Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases. Molecular Medicine. ,vol. 14, pp. 451- 464 ,(2008) , 10.2119/2007-00100.IRVINE
Henryk Barthel, Osama Sabri, None, Florbetaben to trace amyloid-β in the Alzheimer brain by means of PET. Journal of Alzheimer's Disease. ,vol. 26, pp. 117- 121 ,(2011) , 10.3233/JAD-2011-0068
Anders Juréus, Britt-Marie Swahn, Johan Sandell, Fredrik Jeppsson, Allan E. Johnson, Peter Johnström, Jan A. M. Neelissen, Dan Sunnemark, Lars Farde, Samuel P. S. Svensson, Characterization of AZD4694, a novel fluorinated Abeta plaque neuroimaging PET radioligand. Journal of Neurochemistry. ,vol. 114, pp. 784- 794 ,(2010) , 10.1111/J.1471-4159.2010.06812.X
Masahiro Ono, Mamoru Haratake, Morio Nakayama, Yoshikazu Kaneko, Koichi Kawabata, Hiroshi Mori, Mei-Ping Kung, Hank F. Kung, Synthesis and biological evaluation of (E)-3-styrylpyridine derivatives as amyloid imaging agents for Alzheimer's disease. Nuclear Medicine and Biology. ,vol. 32, pp. 329- 335 ,(2005) , 10.1016/J.NUCMEDBIO.2005.01.006
Gjermund Henriksen, Behrooz H Yousefi, Alexander Drzezga, Hans-Jürgen Wester, None, Development and evaluation of compounds for imaging of β-amyloid plaque by means of positron emission tomography European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 35, pp. 75- 81 ,(2008) , 10.1007/S00259-007-0705-X
Agneta Nordberg, Amyloid plaque imaging in vivo: current achievement and future prospects. European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 35, pp. 46- 50 ,(2008) , 10.1007/S00259-007-0700-2
B. J. Bacskai, G. A. Hickey, J. Skoch, S. T. Kajdasz, Y. Wang, G.-f. Huang, C. A. Mathis, W. E. Klunk, B. T. Hyman, Four-dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-β ligand in transgenic mice Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 12462- 12467 ,(2003) , 10.1073/PNAS.2034101100
Allan E. Johnson, Fredrik Jeppsson, Johan Sandell, David Wensbo, Jan A. M. Neelissen, Anders Juréus, Peter Ström, Henrietta Norman, Lars Farde, Samuel P. S. Svensson, AZD2184: a radioligand for sensitive detection of β‐amyloid deposits Journal of Neurochemistry. ,vol. 108, pp. 1177- 1186 ,(2009) , 10.1111/J.1471-4159.2008.05861.X