Selective antagonists at the opiate delta-receptor.
作者： J.S. Shaw , L. Miller , M.J. Turnbull , J.J. Gormley , J.S. Morley
DOI: 10.1016/0024-3205(82)90356-3
关键词:
摘要: Abstract Classical opiate antagonists such as naloxone act predominantly at the mu-receptor and exhibit only weak antagonism delta-receptor. Using two in vitro models - field-stimulated mouse vas deferens guinea pig ileum preparations we have identified novel peptide which selectively competitively reverse effects of opiates delta-receptor, with little or no activity either mu kappa receptors.
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