Design and Synthesis of Novel Sultams: A Family of Non-nucleoside Reverse Transcriptase Inhibitors and Modeling Studies of a Rhodium Catalyst
作者： Riyam Kafri
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参考文章(141)
Fátima Rodríguez-Barrios, Jan Balzarini, Federico Gago, The molecular basis of resilience to the effect of the Lys103Asn mutation in non-nucleoside HIV-1 reverse transcriptase inhibitors studied by targeted molecular dynamics simulations. Journal of the American Chemical Society. ,vol. 127, pp. 7570- 7578 ,(2005) , 10.1021/JA042289G
Hamao Watanabe, Robert L. Gay, Charles R. Hauser, Ortho metalation of N-substituted benzenesulfonamides by excess N-butyllithium. Condensation with carbonyl compounds. Cyclizations Journal of Organic Chemistry. ,vol. 33, pp. 900- 903 ,(1968) , 10.1021/JO01266A111
B. Larder, S. Kemp, Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT). Science. ,vol. 246, pp. 1155- 1158 ,(1989) , 10.1126/SCIENCE.2479983
Kalyan Das, Paul J. Lewi, Stephen H. Hughes, Eddy Arnold, Crystallography and the design of anti-AIDS drugs: conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors Progress in Biophysics & Molecular Biology. ,vol. 88, pp. 209- 231 ,(2005) , 10.1016/J.PBIOMOLBIO.2004.07.001
Lingling Shen, Jianhua Shen, Xiaomin Luo, Feng Cheng, Yechun Xu, Kaixian Chen, Edward Arnold, Jianping Ding, Hualiang Jiang, Steered molecular dynamics simulation on the binding of NNRTI to HIV-1 RT. Biophysical Journal. ,vol. 84, pp. 3547- 3563 ,(2003) , 10.1016/S0006-3495(03)75088-7
Sophie Ugolini, Isabelle Mondor, Quentin J. Sattentau, HIV-1 attachment: another look Trends in Microbiology. ,vol. 7, pp. 144- 149 ,(1999) , 10.1016/S0966-842X(99)01474-2
Kazushi Mashima, Tomoyuki Abe, Kazuhide Tani, Asymmetric Transfer Hydrogenation of Ketonic Substrates Catalyzed by (η5-C5Me5)MCl Complexes (M = Rh and Ir) of (1S,2S)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine Chemistry Letters. ,vol. 1998, pp. 1199- 1200 ,(1998) , 10.1246/CL.1998.1199
Robert Esnouf, Jingshan Ren, Carl Ross, Yvonne Jones, David Stammers, David Stuart, Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors Nature Structural & Molecular Biology. ,vol. 2, pp. 303- 308 ,(1995) , 10.1038/NSB0495-303
Thang Chiu, David Davies, Structure and function of HIV-1 integrase. Current Topics in Medicinal Chemistry. ,vol. 4, pp. 965- 977 ,(2004) , 10.2174/1568026043388547
Stefan G. Sarafianos, Kalyan Das, Chris Tantillo, Arthur D. Clark, Jianping Ding, Jeannette M. Whitcomb, Paul L. Boyer, Stephen H. Hughes, Edward Arnold, Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA The EMBO Journal. ,vol. 20, pp. 1449- 1461 ,(2001) , 10.1093/EMBOJ/20.6.1449