Studies of Isocyanides. I. The Formation of Urethanes and Ureas from Isocyanides
作者： Masaya Okano , Yoshihiko It\={o} , Tatsuya Sh\={o}no , Ryohei Oda
DOI: 10.1246/BCSJ.36.1314
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摘要: The reactions of isocyanides with alkyl hypochlorite, N-bromoamides, and hydroxylamine have been investigated. Cyclohexyl phenyl give t-butyl carbamates (urethanes) by the zinc chloride-catalyzed reaction followed treatment water. An analogous N-bromosuccinimide or N-bromoacetamide in presence a small amount water gives corresponding acylureas. On hydrochloride chloride, cyclohexyl isocyanide affords N-cyclohexylurea.
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