Anxiety and depression following preeclampsia or hemolysis, elevated liver enzymes, and low platelets syndrome. A systematic review.

摘要: Women who suffered from pregnancy complications are at increased risk for anxiety and depression. The aim of this study was to evaluate whether having preeclampsia (PE) or HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome is associated with depression, PE/HELLP an independent factor developing Systematic search on PubMed PsycInfo no time limit. Studies presenting original data, including women a history least one comparison group without PE/HELLP, reporting the results each separately in multivariate regression analysis as variable. Study characteristics outcomes were extracted using prespecified form. If necessary, additional calculations performed. yielded 267 articles, only six being suitable inclusion review. depression (six studies) showed generally positive associations between prevalence severity depressive symptoms. However, three studies not statistically significant. addressing (two did show significant scores. Associations post-traumatic stress investigated four studies, often nonsignificant. Due heterogeneity methods, meta-analysis possible. In most confounder control poor. Evidence mixed but points various forms psychopathology previous PE/HELLP. Causality can, however, be judged adequately.