alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic role.

摘要: Clonidine has proved to be a clinically useful adjunct in clinical anaesthetic practice as well chronic pain therapy because it both and analgesic-sparing activity. The more selective alpha-2 adrenoceptor agonists, dexmedetomidine mivazerol, may also have role providing haemodynamic stability patients who are at risk of peri-operative ischaemia. side-effects hypotension bradycardia limited the routine use agonists. Investigations into molecular pharmacology adrenoceptors elucidated their control wakefulness, blood pressure antinociception. We discuss therapeutic this review. agonists imidazoline receptors which involved central control. Selective now available for antihypertensive agents is discussed.