Gnotobiotic mice inoculated with Firmicutes, but not Bacteroidetes, deteriorate nonalcoholic fatty liver disease severity by modulating hepatic lipid metabolism.

作者: Yi-Hsun Chen , Chien-Chao Chiu , Shao-Wen Hung , Wen-Ching Huang , Yen-Peng Lee

DOI: 10.1016/J.NUTRES.2019.07.001

关键词:

摘要: … Additionally, the effects of Bacteroidetes and Firmicutes on NAFLD still remain unclear. … that Firmicutes and Bacteroidetes may have differential effects on lipid metabolism in the liver, …

参考文章(43)
Guillaume Dalmasso, Hang Thi Thu Nguyen, Yutao Yan, Hamed Laroui, Moiz A. Charania, Saravanan Ayyadurai, Shanthi V. Sitaraman, Didier Merlin, Microbiota Modulates Host Gene Expression via MicroRNAs Gastroenterology. ,vol. 140, pp. S- 663 ,(2011) , 10.1016/S0016-5085(11)62754-6
Georgi Kirovski, Thomas S Weiss, Michael Saugspier, Christoph Dorn, Arndt Hartmann, Marc-Oliver Riener, Claus Hellerbrand, Kathrin Steib, Erwin Gäbele, Glen Kristiansen, Expression of fatty acid synthase in nonalcoholic fatty liver disease. International Journal of Clinical and Experimental Pathology. ,vol. 3, pp. 505- 514 ,(2010)
Srinivasan Dasarathy, Yu Yang, Arthur J. McCullough, Susan Marczewski, Carole Bennett, Satish C. Kalhan, Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis European Journal of Gastroenterology & Hepatology. ,vol. 23, pp. 382- 388 ,(2011) , 10.1097/MEG.0B013E328345C8C7
Luke K. Ursell, Jose C. Clemente, Jai Ram Rideout, Dirk Gevers, J. Gregory Caporaso, Rob Knight, The interpersonal and intrapersonal diversity of human-associated microbiota in key body sites The Journal of Allergy and Clinical Immunology. ,vol. 129, pp. 1204- 1208 ,(2012) , 10.1016/J.JACI.2012.03.010
Anna Kotronen, Anneli Seppälä-Lindroos, Satu Vehkavaara, Robert Bergholm, Keith N. Frayn, Barbara A. Fielding, Hannele Yki-Järvinen, Liver fat and lipid oxidation in humans. Liver International. ,vol. 29, pp. 1439- 1446 ,(2009) , 10.1111/J.1478-3231.2009.02076.X
Kerry L. Donnelly, Coleman I. Smith, Sarah J. Schwarzenberg, Jose Jessurun, Mark D. Boldt, Elizabeth J. Parks, Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease Journal of Clinical Investigation. ,vol. 115, pp. 1343- 1351 ,(2005) , 10.1172/JCI23621
Ahmed Abu-Shanab, Eamonn M. M. Quigley, The role of the gut microbiota in nonalcoholic fatty liver disease Nature Reviews Gastroenterology & Hepatology. ,vol. 7, pp. 691- 701 ,(2010) , 10.1038/NRGASTRO.2010.172
Jan-Wilhelm Kornfeld, Catherina Baitzel, A. Christine Könner, Hayley T. Nicholls, Merly C. Vogt, Karolin Herrmanns, Ludger Scheja, Cécile Haumaitre, Anna M. Wolf, Uwe Knippschild, Jost Seibler, Silvia Cereghini, Joerg Heeren, Markus Stoffel, Jens C. Brüning, Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b Nature. ,vol. 494, pp. 111- 115 ,(2013) , 10.1038/NATURE11793
Marialena Mouzaki, Elena M. Comelli, Bianca M. Arendt, Julia Bonengel, Scott K. Fung, Sandra E. Fischer, Ian D. McGilvray, Johane P. Allard, Intestinal Microbiota in Patients With Nonalcoholic Fatty Liver Disease Hepatology. ,vol. 58, pp. 120- 127 ,(2013) , 10.1002/HEP.26319
Xin Wei Wang, Niels HH Heegaard, Henrik Ørum, MicroRNAs in liver disease Nature Reviews Gastroenterology & Hepatology. ,vol. 10, pp. 542- 552 ,(2013) , 10.1038/NRGASTRO.2013.87