Prevalence and Implications of Subclinical Coronary Artery Disease in Patients With Atrial Fibrillation

作者: Kongkiat Chaikriangkrai , Miguel Valderrabano , Sayf Khaleel Bala , Sama Alchalabi , Edward A. Graviss

DOI: 10.1016/J.AMJCARD.2015.07.041

关键词:

摘要: The objective of this study was to examine prevalence and clinical implications subclinical coronary artery disease (CAD) detected by calcium score (CACS) testing in patients with atrial fibrillation (AF). CACS assessed without history CAD undergoing catheter ablation AF. Age- gender-matched normal sinus rhythm (NSR) presenting chest pain served as controls. Predicted arterial age using the Multi-Ethnic Study Atherosclerosis registry also compared chronologic age. A total 860 (430 AF 430 NSR, 63 ± 10 years, 65% men) were included. Subclinical (CACS >0) 74% (319 430) group. Compared had higher (74% vs 63%; p <0.001). In multivariate analysis, independently associated (hazard ratio 1.60; p = 0.002) but only persistent 2.28; greater than (69 12 64 9 years). CACS-diagnosed identified new potential candidates for statin therapy (12%; 33 267) oral anticoagulation (19%; 40 206) addition CHA2DS2-VASc scores. conclusion, known CAD, significantly those NSR. complimentarily risk factors. Identifying has indications prevention progression stroke.

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