Phytochemicals against drug-resistant microbes

摘要: Bacteria are able to adapt undesirable changes in nutrient availability, environmental conditions and presence of antimicrobial products, as well immunological defenses. Antibiotic resistant bacteria increasingly prevalent consequently new antimicrobials needed control these pathogens. Serious infections caused by that have become commonly used antibiotics a major global healthcare problem the twenty-first century. Development resistance, including multidrug resistance (MDR), is unavoidable because it represents particular aspect general microbial evolution. Many bacterial diseases, which were thought been eradicated from developing countries, might once again serious health problem. There thus an urgent need for products act on novel molecular targets circumvent mechanisms. In this context, plant secondary metabolites (phytochemicals) already demonstrated their potential antibacterials when alone, synergists/potentiators less effective products. Moreover, phytochemicals can be where mechanisms, such MDR, make conventional treatments ineffective also biofilms. The aim chapter cover recent advances phytochemical antibacterial activities against drug-resistant bacteria.