The Last Generation of Pericardial Valves in the Aortic Position: Ten-Year Follow-up in 589 Patients

摘要: Background. The first generation of pericardial valves has been withdrawn from the market because excessively high rates premature failure. With its original design, Carpentier-Edwards valve promised improved results. Methods. In our institution, 589 patients underwent an isolated aortic replacement with a bioprosthesis between July 1984 and December 1993. patients' mean age was 67.5 ± 11.2 years, 49% were in New York Heart Association clinical class III or IV. operative mortality rate 2.3% (14 595). All but 4 followed up for average 4.1 years after their operation, total follow-up 2,408 patient-years. Results. At time study, more than 85% I II. There 79 late deaths. After 10 actuarial survival 71% 7%. Nineteen died valve-related causes (3 endocarditis, 7 thromboembolic complications, 1 structural failure, 8 sudden deaths). freedom death 94% 3% at years. Valve-related complications included 23 episodes (0.9% per patient-year), 14 endocarditis (0.5% 9 reoperations (0.4% failures calcification stenosis (0.2% patient-year). 84% 6%, reoperation 97% 2%, failure 96% 4%. Conclusions. Because low events deterioration no leaflet tears, this prosthesis is outstanding choice who need tissue aged 60 older.