Short-term effects of outdoor air pollution on acute ischaemic stroke occurrence: a case-crossover study in Tianjin, China.

摘要: Objective Ambient air pollution is associated with ischaemic stroke incidence. However, most of the previous studies used stroke-related hospital admission rather than onset itself. This study aimed to evaluate relationship between ambient pollutant exposures and acute based on timing symptom onset. Methods A time-stratified, case-crossover analysis was performed among 520 patients who had admitted Second Hospital Tianjin Medical University (Tianjin, China) 1 April 2018 31 March 2019 (365 days). Daily concentrations particulate matter aerodynamic diameter 2.5 µm, 10 µm (PM10), sulfur dioxide, nitrogen carbon monoxide ozone were obtained from fixed-site monitoring stations. We conditional logistic regression estimate OR 95% CI corresponding an increase in IQR each after adjusting for effects temperature relative humidity. Results Overall, a higher risk found September. During this period PM10 increased (1-day lag: OR=1.49, 95% CI 1.09 2.02; 3-day mean: OR=1.58, 2.29) 34 70 years old. Positive associations also observed OR=1.51, 1.10 2.07; OR=1.57, 1.08 2.29), OR=1.83, 1.16 2.87; OR=1.90, 1.06 3.42) occurrence those hyperlipidaemia. Conclusion Our results suggest that younger people or hyperlipidemia. These findings still need be further investigated.