New restrictions on celecoxib (Celebrex) use and the withdrawal of valdecoxib (Bextra)

作者: J. Cotter

DOI: 10.1503/CMAJ.050456

关键词:

摘要: Reason for posting: Coxibs, the class of NSAIDs that selectively inhibit cyclooxygenase 2 (COX-2), were designed to reduce joint pain and inflammation without causing gastric epithelial adverse effects typical nonselective NSAIDs. Rofecoxib (Vioxx) was withdrawn from market in September

参考文章(2)
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Scott D Solomon, John JV McMurray, Marc A Pfeffer, Janet Wittes, Robert Fowler, Peter Finn, William F Anderson, Ann Zauber, Ernest Hawk, Monica Bertagnolli, None, Cardiovascular Risk Associated With Celecoxib in a Clinical Trial for Colorectal Adenoma Prevention The New England Journal of Medicine. ,vol. 352, pp. 1071- 1080 ,(2005) , 10.1056/NEJMOA050405