Sensor proteins and assay methods

作者: Rhonda Newman , Kurt Vogel , Steven Riddle

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摘要: The present invention relates to biosensors. In some embodiments, the biosensors are modified ligand binding molecules. molecule is a phosphate protein (PBP). molecules labeled be capable of RET, e.g., comprising donor and acceptor moiety. embodiments invention, there detectable change in RET (e.g., FRET) when binds and/or releases phosphate). also provides related methods, reactions assays.

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