A method for treating a disease or disorder of the lung by inhibition of the hedgehog pathway

作者: Victor De Vries , Maria Alicia Curotto de Lafaille

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摘要: The present invention is directed to a method of treating disease or disorder characterised by one more the following: decreased lung function, bronchial hyper-responsiveness, hypersecretion mucus, epithelial cell hyperplasia, smooth muscle hypertrophy, fibrosis inflammation with an antagonist Hedgehog protein, Smoothened, Gli. further provides kits for implementing above and use Gli disorder.

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