Nitrate esters and their use for neurological conditions
作者： Roland J. Boegman , Khem Jhamandas , James N. Reynolds , Brian M. Bennett , Gregory R. J. Thatcher
DOI:
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摘要: Compounds and methods for mitigating neurodegeneration, effecting neuroprotection and/or cognition enhancement in a subject are described. Neurological or cognitive conditions treated by administering to an effective amount of therapeutic compound comprising nitrate ester, pharmaceutically acceptable salt ester thereof.
google.co.uk 参考文章(98)
Fung Hl, Nitrate therapy: is there an optimal substance and formulation? European Heart Journal. ,vol. 12, pp. 9- 12 ,(1991)
Martin Feelisch, Edgar Fritschi, Ralf Kanzler, Klaus Sandrock, Eike Noack, Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof ,(1991)
Biotransformation to nitric oxide of organic nitrates in comparison to other nitrovasodilators European Heart Journal. ,vol. 14, pp. 123- 132 ,(1993) , 10.1093/EURHEARTJ/14.SUPPL.1
Herbert Simon, Helmut Michel, Wolfgang Bartsch, Klaus Strein, Aminopropanol derivatives, processes for the preparation thereof, the use thereof and pharmaceutical compositions containing them ,(1987)
Herbert Simon, Walter-Gunar Friebe, Helmut Michel, Wolfgang Bartsch, Nitroxy amino propanols for treating heart and circulatory diseases ,(1985)
Stuart A. Lipton, David J. Singel, Jonathan S. Stamler, Chapter 29 Nitric oxide in the central nervous system Neural Regeneration. ,vol. 103, pp. 359- 364 ,(1994) , 10.1016/S0079-6123(08)61149-8
Helmut Michel, Wolfgang Bartsch, Nitric acid esters of cyclohexanol derivatives ,(1991)
Feng-Ping Huang, Liang-Fu Zhou, Guo-Yuan Yang, Effects of Mild Hypothermia on the Release of Regional Glutamate and Glycine During Extended Transient Focal Cerebral Ischemia in Rats Neurochemical Research. ,vol. 23, pp. 991- 996 ,(1998) , 10.1023/A:1021088523137
George Y. Wu, Catherine H. Wu, Carrier system and method for the introduction of genes into mammalian cells ,(1990)