Assessing corneal biomechanics with Brillouin spectro-microscopy.
作者： Guillaume Lepert , Ricardo M. Gouveia , Che J. Connon , Carl Paterson
DOI: 10.1039/C5FD00152H
关键词:
摘要: A new Brillouin spectro-microscope was designed and built to investigate the mechanical properties of bovine human corneas. This instrument integrates a single-stage virtually imaged phased array spectrometer with novel adaptive-optics interferometric filter achieve unprecedented rejection elastic background signal. As result, highly-resolved, reproducible data from both thin thick collagen-based materials were obtained. In particular, this technique is capable rigorously measuring relative stiffness different areas corneas, thus providing true non-contact method characterise fundamental features live fixed biological tissue samples.
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